Our Story

When APC was formed in 2011, it was poised to be a game changer in process development. And as it has grown, it has also evolved, leading to the creation of VLE, which is hyper-accelerating the path of specialized medicines to market. Here is a brief overview of our story.

Setting Forth

2011

A Leap of Faith

From the very beginning, our vision has been to revolutionize CMC practices through science and innovation. We began with a single, brave client who saw the passion in Mark and Brian, and put their faith in them to prove what was possible.

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€0
PE or VC
investment
Over €33m
2021
revenue
185
team members
in 2022

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1 Team
1 Team on a mission - accelerate the delivery of medicines
50:50
50:50 Female/Male in management positions
75m €
75m Euro of world class technology infrastructure

Breaking Through

VLE Scientist at Work
VLE Scientists at Work
2015

Leading with Innovation

We quickly made a name for ourselves by providing innovative solutions to some of the most complex and chronic problems in process development.

From self-optimizing bioreactors to simulated mixing environments, APC has developed a host of extraordinary breakthroughs for clients.

See 7 Big Breakthroughs

A Massive Expansion

xx
people
xx
capital
xx
clients
xx
key technologies

VLE Quiz

APC’s first research project in 2011 solved a manufacturing throughput problem for a medicine that treated which area of illness?

High-Powered Process Development

2018

Pioneering the Use of Microcarriers

Our process development expertise never settles for existing methods, especially if it means potential life-saving therapies won’t reach patients fast enough. Making clients’ gene therapies, viral vaccines and viral immunotherapies commercially viable required the development of multiple novel approaches using microcarrier beads in single-use bioreactors.

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Digital Transparency

2020

Our Process at Your Fingertips

There are no smoke and mirrors with APC & VLE. From process development through manufacturing, clients have total clarity with iACHIEVE, our collaborative data management platform for maintaining active communication and robust digital documentation. iACHIEVE turns typically painstaking tech transfers into effortless onramps to manufacturing and regulatory review.

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90%
PhD qualified
team
60k
sq ft headquarters
80%
export driven

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> 100
Over 100 of the world’s most innovative clients
> 1000
Over 1000 medicines researched
+200
+200 scientists, engineers and CMC/GMP experts

On the Global Stage

2021

Next-Generation Vaccine Development

At the start of the pandemic, we were eager to assist the global community by expediting the development of a coronavirus vaccine. An Taoiseach Micheál Martin visited visited APC and VLE to tour our state-of-the-art facility, meet our team of world-class scientists and manufacturing engineers, and promote Ireland’s global standing.

VLE Quiz

At VLE’s inception how many nationalities were working across our combined APC & VLE teams?

Beyond Process Development

VLE Core Team Members Image

INTERVIEW

2022

VLE: The Medicine Accelerator

Years of optimizing and perfecting process development have surfaced critical flaws in manufacturing. So we created VLE to combine forces with APC, creating a true medicine accelerator that slashes the timeline to patients by utilizing an adaptive, flexible manufacturing approach rather than pre-set, standardized methods.

Read The Interview

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Over 1 Trn
Customer Market
Cap
Over €120m
revenue derived
from Platforms and
Customers
Over €5bn
market opportunity
for CGT & Vaccines
Tech based Manufacture

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22
22 nationalities on our team
60
60 CMC-to-GMP programs digitally powered by iACHIEVE
10 years
10 years transforming how medicines are made

Science-First Manufacturing

12

Where We Are Today

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Read The Interview
VLE Scientists working with Bioreactor

Where We Are Today

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View Audio Transcript
12

Where We Are Today

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Read The Interview

VLE Changes the Game

VLE Scientists working with Bioreactor

INTERVIEW

Today

Science-Led Manufacturing

VLE is eliminating the traditional tech transfer by having our scientists and engineers lead the knowledge transfer into manufacturing. Every day we strive to recognize opportunities to create a more streamlined flow from process development to manufacturing, ultimately accelerating the delivery to patients.

Read The Interview

VLE Quiz

The laboratories in our state of the art facility are all named after what?

Looking Forward

Extending the Value Chain

With APC at the helm of process development, VLE extends the value chain for our clients by accelerating GMP manufacturing through all phases of clinical trials. We’re reducing costs and shortening timelines while optimizing manufacturing for trials. Our motivation isn’t filling tanks—it’s changing lives.

Science-First Manufacturing

12

Where We Are Today

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Read The Interview
VLE Scientists working with Bioreactor

Where We Are Today

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Leo vel fringilla est ullamcorper eget nulla facilisi.

View Audio Transcript
12

Where We Are Today

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Leo vel fringilla est ullamcorper eget nulla facilisi.

Read The Interview

Science-First Manufacturing in Action

VLE scientists working together